A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has
A Biogen facility in Cambridge, Massachusetts. Brian Snyder | Reuters Biogen plans to advance an experimental drug for Alzheimer's disease to late-stage testing despite disappointing mid-stage trial data, the company said Thursday. Biogen said its experimental drug that targets tau, a protein associated with the memory-robbing disease, failed to show better responses at higher doses.
A cruise ship outbreak of hantavirus has rattled the public and reignited fears of another global health scare as passengers disperse across multiple countries, including the U.S. The World Health Organization reported 11 cases linked to the outbreak as of Tuesday, nine of which it confirmed, including three deaths. No Americans have tested positive as
President Donald Trump onstage at the Treasury Department's Trump Accounts Summit, in Washington, Jan. 28, 2026. Kevin Lamarque | Reuters A version of this article first appeared in CNBC's Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox. With
As AI begins to interact with the physical world, new types of labs are working to build world models that could be used to operate physical robotics or model objects in physical space. Unlike large language models, there isn’t an easy source of data for those models, which has left many labs scrambling to assemble
Anthropic is looking to court smaller companies. To that end, the company announced Wednesday the launch of Claude for Small Business, a new suite of services designed for customers who less resemble Walmart and Starbucks and more resemble the local hardware store or coffee shop. So far, much of the most intensive AI adoption has